Guanosine 5'-diphosphate (sodium salt hydrate)

Guanosine 5'-diphosphate (GDP) is a purine nucleotide and biosynthetic precursor of guanosine 5'-triphosphate (GTP, Cay-16060). It has been used to study the conformations of GTPases. GDP (100 µM) activates sulfonylurea receptor 2B (SUR2B) linked to the inward-rectifier potassium channel 6.1 (Kir6.1) in HEK293T cells in a patch-clamp assay.Formal Name: guanosine, 5'-(trihydrogen diphosphate), disodium salt, hydrate. Synonyms: GDP. Molecular Formula: C10H13N5O11P2 . 2Na [XH2O]. Formula Weight: 487.2. Purity: >90%. Formulation: (Request formulation change), A solid. Solubility: PBS (pH 7.2): 10 mg/ml. lambdamax: 254 nm. SMILES: O=P(OP(O)([O-])=O)([O-])OC[C@@H]1[C@@H](O)[C@@H](O)[C@]([H])(N2C=NC3=C2NC(N)=NC3=O)O1.[Na+].[Na+].O. InChi Code: InChI=1S/C10H15N5O11P2.2Na.H2O/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(25-9)1-24-28(22,23)26-27(19,20)21,,,/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H2,19,20,21)(H3,11,13,14,18),,,1H2/q,2*+1,/p-2/t3-,5-,6-,9-,,,/m1.../s1. InChi Key: SYNIMEQECSCTMW-CYCLDIHTSA-L.