(±)-Goitrin

(±)-Goitrin is a goitrogen and antithyroid compound that has been found in plants of the Brassica family. Dietary administration of (±)-goitrin (0.06-0.18% w/w) increases thyroid weight and decreases thyroid radioactive iodine uptake in rats fed a low-iodine diet. It also increases thyroid weight in chicks in a dose-dependent manner. (±)-Goitrin inhibits norepinephrine formation by bovine dopamine-beta-hydroxylase in vitro when used at a concentration of 0.2 mM.Formal Name: 5-ethenyl-2-oxazolidinethione. CAS Number: 13190-34-6. Synonyms: DL-Goitrin, (R,S)-Goitrin. Molecular Formula: C5H7NOS. Formula Weight: 129.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. lambdamax: 246 nm. SMILES: S=C1OC(C=C)CN1. InChi Code: InChI=1S/C5H7NOS/c1-2-4-3-6-5(8)7-4/h2,4H,1,3H2,(H,6,8). InChi Key: UZQVYLOFLQICCT-UHFFFAOYSA-N.