Glycyrrhizic Acid (ammonium salt)

Glycyrrhizic acid is a natural triterpenoid saponin that can be isolated from the root of licorice. It is an agonist of the human sweet taste receptor and is used as a flavorant. Glycyrrhizic acid has diverse cellular effects at low doses, including antioxidant, anti-inflammatory, antimicrobial, and antiviral actions. Presumably through its role as an antioxidant, glycyrrhizic acid alters signaling through a variety of signaling pathways, impacting pathologies such as metabolic syndrome, fibrosis, and ultraviolet-B-induced skin damage in cellular and animal models.Formal Name: 20beta-carboxy-11-oxo-30-norolean-12-en-3beta-yl 2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid, monoammonium salt. CAS Number: 53956-04-0. Synonyms: Ammonium Glycyrrhizinate, Glycyrrhizin, Glycyrrhizinate, NSC 2800, NSC 35348. Molecular Formula: C42H62O16 . NH3. Formula Weight: 840.0. Purity: >80%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 1 mg/mL, DMSO: 20 mg/mL, PBS (pH 7.2): 1 mg/mL. lambdamax: 249 nm. SMILES: O=C1[C@@]2([H])[C@](CC[C@]3([H])[C@]2(C)CC[C@H](O[C@@]4([H])O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]4O[C@@]5([H])[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O5)C3(C)C)(C)[C@]6(C)CC[C@@]7(C)CC[C@@](C(O)=O)(C)C[C@@]7([H])C6=C1.N. InChi Code: InChI=1S/C42H62O16.H3N/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50,/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7. InChi Key: ILRKKHJEINIICQ-OOFFSTKBSA-N. Origin: Plant/Glycyrrhiza glabra.