Glycodeoxycholate Sodium

Description: The mechanism by which Glycodeoxycholate Sodium induces apoptosis in hepatocytes is related to DNA cleavage by endonucleases. It is a secondary bile acid produced by the action of enzymes present in the microflora of the colonic environment. Target: Others, Endogenous Metabolite. Smiles: [Na+].C[C@H](CCC(=O)NCC([O-])=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C. References: Kwo P, et al. Nuclear serine protease activity contributes to bile acid-induced apoptosis in hepatocytes. Am J Physiol. 1995 Apr,268(4 Pt 1):G613-21.