Glufosinate (ammonium salt)

Glufosinate is a broad-spectrum herbicide and a racemic mixture of L-phosphinothricin, a phytotoxic compound, and D-phosphinothricin, its inactive enantiomer. It is an irreversible inhibitor of glufosinate synthetase 1 (GS1) and GS2 (Kis = 1.1. and 4.8 µM, respectively), enzymes that are required for nitrogen metabolism in plants. Glufosinate induces the production of reactive oxygen species (ROS) and lipid peroxidation in plant cell membranes. It reduces dry biomass of the weeds E. canadensis and L. rigidum with ED50 values of 26 and 763 g/hectare, respectively. Glufosinate has no observed adverse effects in rats and mice when administered at doses of 4.1 and 17 mg/kg per day for three months. Formulations containing glufosinate have been used as foliar herbicides in agriculture.Formal Name: 2-amino-4-(hydroxymethylphosphinyl)-butanoic acid, monoammonium salt. CAS Number: 77182-82-2. Synonyms: HOE 00661, HOE 39866. Molecular Formula: C5H11NO4P . NH4. Formula Weight: 198.2. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 10 mg/ml. SMILES: OC(C(CCP(C)([O-])=O)N)=O.[NH4+]. InChi Code: InChI=1S/C5H12NO4P.H3N/c1-11(9,10)3-2-4(6)5(7)8,/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10),1H3. InChi Key: ZBMRKNMTMPPMMK-UHFFFAOYSA-N.