Glaucine

Description: Glaucine has antitussive, antioxidative potential and antiviral activities, it may be an anti-arthritic agent, it can enhance LPS and zymosan-induced IL-10 production. Glaucine can inhibit the migration and invasion of human breast cancer cells by MMP-9 inhibitory activity, attenuating IkappaBalpha and NF-kappaB activities. Target: Adrenergic Receptor, Calcium Channel, Dopamine Receptor, Influenza Virus, PDE. Smiles: O(C)C1=C2C=3[C@](CC=4C2=CC(OC)=C(OC)C4)(N(C)CCC3C=C1OC)[H]. References: Meyer G M J , Meyer M R , Wink C S D , et al. Studies on the in vivo contribution of human cytochrome P450s to the hepatic metabolism of glaucine, a new drug of abuse[J]. Biochemical Pharmacology, 2013, 86(10):1497-1506.