Ganoderic acid D

Description: 1. Ganoderic acid D is one of the major components in Ganoderma triterpenes. 2. Ganoderic acid D treatment for 48h inhibits the proliferation of HeLa human cervical carcinoma cells with an IC(5) value of 17.3 +/- .3 microM. Target: Sirtuin, Apoptosis. Smiles: [H][C@@]12C[C@H](O)C3=C(C(=O)C[C@]4(C)[C@H](CC(=O)[C@@]34C)[C@H](C)CC(=O)CC(C)C(O)=O)[C@@]1(C)CCC(=O)C2(C)C. References: Yue Q X , Cao Z W , Guan S H , et al. Proteomics Characterization of the Cytotoxicity Mechanism of Ganoderic Acid D and Computer-automated Estimation of the Possible Drug Target Network[J]. Molecular & Cellular Proteomics, 2008, 7(5):949-961.