gamma-Mangostin

Description: 1. gamma-Mangostin (Normangostin) as a preventive agent of the metabolic syndrome. 2. Gamma-Mangostin has free radical scavenging activity, and antiproliferative and apoptotic activity in HepG2 cells. 3. Gamma-Mangostin could serve as a micronutrient for colon cancer prevention and is a potential lead compound for the development of anti-colon cancer agents. 4. Gamma-Mangostin may acts as an antihypertensive agent , by causing vasorelaxation which is mediated via the NO-cGMP pathway. Target: 5-HT Receptor, Others. Smiles: CC(C)=CCc1c(O)cc2oc3cc(O)c(O)c(CC=C(C)C)c3c(=O)c2c1O. References: Chang H F , Wu C H , Yang L L . Antitumour and free radical scavenging effects of gamma-mangostin isolated from\r, Garcinia mangostana\r, pericarps against hepatocellular carcinoma cell[J]. Journal of Pharmacy and Pharmacology, 2013, 65(9):1419-1428.