Gabaculine HCl

Description: Gabaculine is an irreversible inhibitor of GABA transaminase (GABA-T, Ki: 2.9 µM). Gabaculine alters plastid development and differentially affects the abundance of plastid-encoded DPOR and nuclear-encoded GluTR. Target: Others. Smiles: Cl.O=C(O)C1=CC=CC(N)C1. References: Bellucci M, De Marchis F, Ferradini N, Pompa A, Veronesi F, Rosellini D. A mutant Synechococcus gene encoding glutamate 1-semialdehyde aminotransferase confers gabaculine resistance when expressed in tobacco plastids. Plant Cell Rep. 2015 Dec,34(12):2127-36. doi: 10.1007/s00299-015-1856-z. Epub 2015 Aug 12. PubMed PMID: 26265112.