FlAsH-EDT2

FlAsH-EDT2 is a pro-fluorescent, membrane-permeable biarsenical compound that binds covalently to a tetracysteine sequence (CCPGCC), which is engineered into target proteins. It binds proteins that have the CCPGCC tag almost immediately after translation. FlAsH-EDT2 is commonly used to study protein trafficking, folding, and interactions in living cells or cell lysates. This green-emitting fluorophore is excited at 508 nm, with emission at 528 nm.Formal Name: 4',5'-bis(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxy-spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one. CAS Number: 212118-77-9. Synonyms: Fluorescein Arsenical Helix Binder, Lumio Green. Molecular Formula: C24H18As2O5S4. Formula Weight: 664.5. Purity: >98%. Emission: 528 nm. Excitation: 508 nm. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 15 mg/ml, DMSO: 20 mg/ml, DMSO:PBS (pH 7.2) (1:10): 0.09 mg/ml. lambdamax: 515 nm. SMILES: OC1=C([As]2SCCS2)C3=C(C4(C(C=CC=C5)=C5C(O4)=O)C6=CC=C(O)C([As]7SCCS7)=C6O3)C=C1. InChi Code: InChI=1S/C24H18As2O5S4/c27-17-7-5-15-21(19(17)25-32-9-10-33-25)30-22-16(6-8-18(28)20(22)26-34-11-12-35-26)24(15)14-4-2-1-3-13(14)23(29)31-24/h1-8,27-28H,9-12H2. InChi Key: AJNUQUGWNQHQDJ-UHFFFAOYSA-N.