Erythro-sphingosine, (+)-

Description: Erythro-sphingosine, (+)- is a cell-permeable and reversible inhibitor of protein kinase C (IC50: 12 µM) and enhances Src kinase activity. Target: Others. Smiles: C(=C/CCCCCCCCCC CCC)\[C@@H]([C@@H](CO)N)O. References: Kong JN, Zhu Z, Itokazu Y, Wang G, Dinkins MB, Zhong L, Lin HP, Elsherbini A, Leanhart S, Jiang X, Qin H, Zhi W, Spassieva SD, Bieberich E. Novel function of ceramide for regulation of mitochondrial ATP release in astrocytes. J Lipid Res. 2018 Mar,59(3):488-506. doi: 10.1194/jlr.M081877. Epub 2018 Jan 10. PubMed PMID: 29321137, PubMed Central PMCID: PMC5832933.