EFdA-TP 3TEA

Description: EFdA-TP 3TEA is the salt form of EFdA-TP.EFdA-TP 3TEA is a nucleoside analog that is a novel, potent, and selective nucleoside reverse transcriptase (RT) inhibitor that inhibits HIV-1 reverse transcriptase by multiple mechanisms, thereby increasing its drug resistance. Target: Reverse Transcriptase. Smiles: CCN(CC)CC.O=P(O)(O)OP(OP(OC[C@]1(O[C@H](C[C@@H]1O)N2C3=NC(F)=NC(N)=C3N=C2)C#C)(O)=O)(O)=O.CCN(CC)CC.CCN(CC)CC. References: Eleftherios Michailidis, et al. 4'-Ethynyl-2-fluoro-2'-deoxyadenosine (EFdA) inhibits HIV-1 reverse transcriptase with multiple mechanisms. J Biol Chem. 2014 Aug 29,289(35):24533-48.