DUPA

Description: DUPA (N,N''-Carbonylbis[L-glutamic acid]) is used as the targeting moiety to actively deliver DTX for treatment of Prostate-Specific Membrane Antigen (PSMA) expressing prostate cancer. Target: Ligands for Target Protein for PROTAC, Others. Smiles: [C@H](NC(N[C@@H](CCC(O)=O)C(O)=O)=O)(CCC(O)=O)C(O)=O. References: Peng ZH, et al. Spacer length impacts the efficacy of targeted docetaxel conjugates in prostate-specific membrane antigen expressing prostate cancer. J Drug Target. 2013 Dec,21(10):968-80.