Dopastin

Dopastin is a bacterial metabolite that has been found in Pseudomonas and an inhibitor of dopamine beta-hydroxylase (Ki = 4.7 µM). In vivo, dopastin (20 mg/kg) reduces mean systolic blood pressure in spontaneously hypertensive rats. Dopastin also inhibits the germination of barley seeds (IC50 = 47 µM).Formal Name: (2E)-N-[(2S)-2-(hydroxynitrosoamino)-3-methylbutyl]-2-butenamide. CAS Number: 37134-80-8. Synonyms: NSC 252927. Molecular Formula: C9H17N3O3. Formula Weight: 215.3. Purity: >90%. Formulation: (Request formulation change), A solid. SMILES: O=C(NC[C@@H](N(N=O)O)C(C)C)/C=C/C. InChi Code: InChI=1S/C9H17N3O3/c1-4-5-9(13)10-6-8(7(2)3)12(15)11-14/h4-5,7-8,15H,6H2,1-3H3,(H,10,13)/b5-4+/t8-/m1/s1. InChi Key: FJUBKTNNXRFHFD-WTSVBCDHSA-N. Origin: Bacterium/Pseudomonas.