Dodecylphosphocholine

Dodecylphosphocholine is a detergent that is commonly used for membrane protein structure determination using NMR. It has also been used to generate membrane mimetic micelles and to characterize pore formation by the influenza M2 transmembrane domain within a synthetic membrane. Dodecylphosphocholine micelles induce amyloid fibril formation by the prion protein (PrP) beta-strand (PrP (110-136)). Dodecylphosphocholine has a critical micelle concentration (CMC) of approximately 1.5 mM.Formal Name: 2-[[(dodecyloxy)hydroxyphosphinyl]oxy]-N,N,N-trimethyl-ethanaminium, inner salt. CAS Number: 29557-51-5. Synonyms: n-Dodecylphosphocholine. Molecular Formula: C17H38NO4P. Formula Weight: 351.5. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 16 mg/ml, DMSO: 16 mg/ml, Ethanol: 15 mg/ml, PBS (pH 7.2): 25 mg/ml. SMILES: C[N+](C)(C)CCOP(OCCCCCCCCCCCC)([O-])=O. InChi Code: InChI=1S/C17H38NO4P/c1-5-6-7-8-9-10-11-12-13-14-16-21-23(19,20)22-17-15-18(2,3)4/h5-17H2,1-4H3. InChi Key: QBHFVMDLPTZDOI-UHFFFAOYSA-N.