Dimethomorph

Dimethomorph is a morpholine fungicide that inhibits fungal cell wall formation. It inhibits mycelial growth of the oomycete fungi P. citrophthora, P. parasitica, P. capsici, and P. infestans (EC50s = 0.14, 0.38, C. vulgaris or S. obliquus in vitro (EC50s = 47.46 and 44.87 µg/ml, respectively). It inhibits androgen receptor (AR) activity in a reporter assay in MDA-kb2 human breast cancer cells but not in a yeast antiandrogen screen (IC20s = 0.263 and 38.5 µM, respectively). It is not toxic to rats (LD50 = 3,900 mg/kg) or goldfish (C. auratus, LC50 = >32 µg/ml). Formulations containing dimethomorph have been used in the control of fungi in agriculture.Formal Name: 3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-1-(4-morpholinyl)-2-propen-1-one. CAS Number: 110488-70-5. Molecular Formula: C21H22ClNO4. Formula Weight: 387.9. Purity: >95% (mixture of cis and trans isomers). Formulation: (Request formulation change), A solid. Solubility: Chloroform: Soluble, Methanol: Soluble. lambdamax: 244 nm. SMILES: COC1=CC=C(/C(C2=CC=C(Cl)C=C2)=C/C(N3CCOCC3)=O)C=C1OC. InChi Code: InChI=1S/C21H22ClNO4/c1-25-19-8-5-16(13-20(19)26-2)18(15-3-6-17(22)7-4-15)14-21(24)23-9-11-27-12-10-23/h3-8,13-14H,9-12H2,1-2H3/b18-14+. InChi Key: QNBTYORWCCMPQP-NBVRZTHBSA-N.