Dichlorvos

Dichlorvos is an organophosphate insecticide and inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE, IC50s = 269 and 44 nM, respectively). It also binds to the M2 muscarinic receptor in rat heart homogenates. Dichlorvos is lethal to 4-week old German cockroach (B. germanica) nymphs (LD50 = 0.108 µg per insect) and silkworms (B. mori) in third instar (LC50 = 6.63 mg/L) after 24 hours. It is lethal to zebrafish (D. rerio) embryos (LC50 = 39.75 mg/L after 24 hours) and decreases swimming activity of larvae 6 days after fertilization when administered at a concentration of 25 mg/L in tank water. Dichlorvos (150 ppm for 80 weeks) also increases the incidence of benign and malignant neoplasms in male rats from 47 to 88% as compared to controls. Formulations containing dichlorvos have been used as insecticides and miticides in agriculture, as well as in aquatic, commercial, industrial, and residential areas.Formal Name: phosphoric acid, 2,2-dichloroethenyl dimethyl ester. CAS Number: 62-73-7. Synonyms: DDVP, Dichlorovinyl Dimethyl Phosphate, NSC 6738. Molecular Formula: C4H7Cl2O4P. Formula Weight: 221.0. Purity: >98%. Formulation: (Request formulation change), A neat oil. Solubility: Chloroform: Soluble, Ethyl Acetate: Soluble, Methanol: Soluble, Water: Soluble. SMILES: Cl/C(Cl)=C/OP(OC)(OC)=O. InChi Code: InChI=1S/C4H7Cl2O4P/c1-8-11(7,9-2)10-3-4(5)6/h3H,1-2H3. InChi Key: OEBRKCOSUFCWJD-UHFFFAOYSA-N.