DETA NONOate

White to off-white solid. Soluble in water. Nitric oxide (NO) donor. The slow release of NO allows the use in experiments investigating the effects of prolonged constant NO delivery to cells and tissues, The half-life time is 20 hours at 37°C and 56 hours at 22-25°C in 0.1M phosphate buffer, pH 7.4. Liberates 2 mol of NO per mol of parent compound. Decomposition of NONOates is nearly instantaneous at pH 5.0.