Decatromicin B

Description: Decatromicin B is a bacterial metabolite that has been found in Actinomadura. It is active against Gram-positive bacteria, including several strains of S. aureus (MICs = 0.39-0.78 µg/ml), two strains of methicillin-resistant S. aureus (MRSA, MICs = 0.39 and 0.78 µg/ml), as well as M. luteus, B. subtilis, and C. bovis (MICs = 0.78, 0.78, and 6.25 µg/ml, respectively). Target: Others. Smiles: [H][C@]12CC=CC\C(C)=C/[C@@]3(C)C=C([C@@H](CC)C[C@]33OC(=O)C(=C3O)C(=O)[C@@]1(CC)[C@]1([H])CC[C@H](C)[C@H](O[C@H]3C[C@@H](O)[C@H](NC(=O)c4[nH]c(Cl)cc4Cl)[C@@H](C)O3)[C@@]1([H])C=C2)C(O)=O , c:7,11,22,63,