DEAE-dextran," MW 500000 hydrochloride

Description: DEAE-dextran", MW 500000 hydrochloride (DEAE-dextran, MW 500000 hydrochloride, from bacterial [Leuconostoc mesenteroides]) is a high molecular weight," positively charged polymer that notably enhances the uptake of viral RNA by cultured cells. It is employed in """"tumor immunity"""" RNA-spleen cell transfer systems", significantly prolonging the lifespan of tumor-bearing animals, comparable to those with active immunity. DEAE-dextran acts as a nucleic acid complexing agent, forming composite particles with DNA/RNA, and is widely used in gene delivery. Additionally," it serves as a coating for liposomes.""