D-Fructose-13C6

D-Fructose-13C6 is intended for use as an internal standard for the quantification of D-fructose by GC- or LC-MS. D-Fructose is a ubiquitous monosaccharide and is derived, in addition to glucose, from the breakdown of sucrose by sucrase in the intestine. It is a precursor in the biosynthesis of D-fructose-1,6-bisphosphate (Cay-20516), which is an intermediate in the production of D-glucose via gluconeogenesis. Deficiencies in the enzymes that metabolize D-fructose are inborn errors of metabolism that range from benign, for fructokinase deficiency, to severe, for hereditary fructose intolerance, if D-fructose, sucrose, and sorbitol are not eliminated from the diet. Increased consumption of D-fructose is associated with obesity, dyslipidemia, and impaired insulin sensitivity.Formal Name: D-fructose-1,2,3,4,5,6-13C6. CAS Number: 201595-65-5. Synonyms: D-(-)-Fructose-13C6, D-(-)-Levulose-13C6. Molecular Formula: [13C]6H12O6. Formula Weight: 186.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 1 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: O[13CH2][13C@@H](O)[13C@@H](O)[13C@H](O)[13C]([13CH2]O)=O. InChi Code: InChI=1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h3,5-9,11-12H,1-2H2/t3-,5-,6-/m1/s1/i1+1,2+1,3+1,4+1,5+1,6+1. InChi Key: BJHIKXHVCXFQLS-HJLYHLTLSA-N.