CZC-8004

CZC-8004 is an aminopyrimidine that binds a range of tyrosine kinases, including ABL, BTK, FAK, FER, JAK1, SRC, SYK, TEC, TNK1, TYK2, and YES. It inhibits these kinases at low micromolar concentrations and can be immobilized to capture and purify these enzymes.Formal Name: N2-[4-(aminomethyl)phenyl]-5-fluoro-N4-phenyl-2,4-pyrimidinediamine. CAS Number: 916603-07-1. Synonyms: Dianilinopyrimidine-01. Molecular Formula: C17H16FN5. Formula Weight: 309.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 2 mg/ml, DMSO: 5 mg/ml, DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml, Ethanol: 0.1 mg/ml. lambdamax: 274, 321 nm. SMILES: FC1=CN=C(NC2=CC=C(CN)C=C2)N=C1NC3=CC=CC=C3. InChi Code: InChI=1S/C17H16FN5/c18-15-11-20-17(22-14-8-6-12(10-19)7-9-14)23-16(15)21-13-4-2-1-3-5-13/h1-9,11H,10,19H2,(H2,20,21,22,23). InChi Key: UKOHFWNBTUJMMN-UHFFFAOYSA-N.