Cysteamine (hydrochloride)

Cysteamine is a stable aminothiol with radioprotective activities. It reduces ionizing radiation-induced death and chromosomal damage in mice in a dose-dependent manner. Cysteamine binds rapidly and temporarily to plasma proteins upon administration and this activity is directly correlated to its radioprotective effects. In vitro, 0.1 mM cysteamine depletes 90% of free cystine from cystinotic fibroblasts. Formulations containing cysteamine have been used to treat nephropathic cystinosis and reduce glomerular deterioration in humans.Formal Name: 2-amino-ethanethiol, monohydrochloride. CAS Number: 156-57-0. Synonyms: CI-9148, beta-Mercaptoethylamine. Molecular Formula: C2H7NS . HCl. Formula Weight: 113.6. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 5 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: NCCS.Cl. InChi Code: InChI=1S/C2H7NS.ClH/c3-1-2-4,/h4H,1-3H2,1H. InChi Key: OGMADIBCHLQMIP-UHFFFAOYSA-N.