Cyclopropavir

Description: Cyclopropavir (Filociclovir, MBX-400) is a compound of broad-spectrum anti-herpesvirus. It has good antiviral activity against cytomegalovirus (CMV), herpes simplex virus (HHV)-6 and HHV-8 (EC50s: 0.7 µM to 8 µM). Target: Others. Smiles: C(O)C1(CO)/C(=C\N2C3=C(N=C2)C(=O)N=C(N)N3)/C1. References: Kern ER, et al. In vitro activity and mechanism of action of methylenecyclopropane analogs of nucleosides against herpesvirus replication. Antimicrob Agents Chemother. 2005 Mar,49(3):1039-45.