Crizotinib

Artikelnummer	Größe	Datenblatt	Manual	SDB	Lieferzeit	Menge	Preis
CDX-C0699-M010	10 mg		-	-	3 - 9 Werktage*		122,00 €
CDX-C0699-M050	50 mg		-	-	3 - 9 Werktage*		367,00 €

Bei Fragen nutzen Sie gerne unser Kontaktformular.
Bestellen Sie auch per E-Mail: info@biomol.com
Größere Menge gewünscht? Bulk-Anfrage

White to off-white powder. Soluble in choroform, DMSO or methanol. Chemical. CAS: 877399-52-5.... mehr

Menü schließen

Produktinformationen "Crizotinib"

White to off-white powder. Soluble in choroform, DMSO or methanol. Chemical. CAS: 877399-52-5. Formula: C21H22Cl2FN5O. MW: 450.34. Synthetic. Crizotinib is an anticancer drug. It is a potent, orally bioavailable, ATP-competitive inhibitor of the receptor tyrosine kinases (RTKs) c-Met (hepatocyte growth factor receptor), anaplastic lymphoma kinase (ALK) and ROS1 (c-ros oncogene 1). Selective for c-MET and ALK against >120 different kinases. Displays antitumor efficacy in multiple tumor models, inhibits c-MET-dependent proliferation, migration and invasion of human tumor cells in vitro. Orally bioavailable. Crizotinib was approved for treatment of a subtype of nonsmall-cell lung cancer (NSCLC) with ALK fusion mutations.

Schlagworte:	(R)-3-[1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine, PF 2341066, PF-02341066, PF02341066, Xalkori
Hersteller:	Chemodex
Hersteller-Nr:	C0699

Eigenschaften

MW:	450,34 D
Formel:	C21H22Cl2FN5O
Reinheit:	>98% (HPLC)
Format:	Solid

Datenbank Information

CAS :

877399-52-5| Passende Produkte

Handhabung & Sicherheit

Lagerung:	+4°C
Versand:	+20°C (International: +20°C)
Signalwort:	Warning
GHS-Piktogramme:
H-Sätze:	H317, H319, H341, H400
P-Sätze:	P273, P280, P305+P351+P338