Creatine (hydrate)

Creatine is a derivative of the amino acid glycine. It is produced from glycine and L-arginine by arginine:glycine amidinotransferase (AGAT) and guanidinoacetate N-methyltransferase (GAMT) via a guanidinoacetate intermediate. Creatine circulates in the blood and enters tissues via the creatine transporter. In tissues, it is phosphorylated to creatine phosphate (Cay-35598, Cay-37803), which is used as a reservoir of phosphoryl groups that can be transferred to ATP for the first few seconds of energy consumption, particularly in high-energy consumption tissues such as the brain and skeletal muscle. Decreased brain levels of creatine are associated with inborn errors of creatine metabolism characterized by deficiency of AGAT, GAMT, or the creatine transporter.Formal Name: N-(aminoiminomethyl)-N-methyl-glycine, monohydrate. CAS Number: 6020-87-7. Molecular Formula: C4H9N3O2 . H2O. Formula Weight: 149.1. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMSO: 1 mg/ml, PBS (pH 7.2): 5 mg/ml. SMILES: O=C(CN(C)C(N)=N)O.O. InChi Code: InChI=1S/C4H9N3O2.H2O/c1-7(4(5)6)2-3(8)9,/h2H2,1H3,(H3,5,6)(H,8,9),1H2. InChi Key: MEJYXFHCRXAUIL-UHFFFAOYSA-N.