CNT2 inhibitor-1

Description: CNT2 inhibitor-1 is a potent inhibitor of concentrative nucleoside transporter 2 (CNT2) with an IC50 of 640 nM for hCNT2. Target: Others. Smiles: Nc1ncnc2n([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c(NCc3ccc(cc3)-c3ccccc3)nc12. References: Tatani K, et al. Identification of 8-aminoadenosine derivatives as a new class of human concentrative nucleoside transporter 2 inhibitors. ACS Med Chem Lett. 2015 Jan 28,6(3):244-8.