CNQX

Description: CNQX (FG9065) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 µM for AMPA and kainate receptors, respectively). Target: GluR, iGluR. Smiles: [O-][N+](=O)c1cc2[nH]c(=O)c(=O)[nH]c2cc1C#N. References: Blake J F , Brown M W , Collingridge G L . CNQX blocks acidic amino acid induced depolarizations and synaptic components mediated by non-NMDA receptors in rat hippocampal slices[J]. Neuroscience letters, 1988, 89(2):182-186.