Clomipramine (hydrochloride)

Clomipramine is a tricyclic antidepressant, the 3-chlorinated derivative of imipramine (Cay-15890). Like imipramine, clomipramine potently inhibits serotonin and norepinephrine reuptake (Kis = 7.4 and 96 nM, respectively). It also is an antagonist at histamine, muscarinic acetylcholine, alpha1-adrenergic, and dopamine receptors (Kds = 31, 37, 38, and 190 nM for H1, M1, alpha1, and D2, respectively).Formal Name: 3-chloro-10,11-dihydro-N,N-dimethyl-5H-dibenz[b,f]azepine-5-propanamine, monohydrochloride. CAS Number: 17321-77-6. Molecular Formula: C19H23ClN2 . HCl. Formula Weight: 351.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 3 mg/ml, DMSO: 10 mg/ml, Ethanol: 10 mg/ml, PBS (pH 7.2): 0.5 mg/ml. SMILES: ClC1=CC2=C(C=C1)CCC3=C(C=CC=C3)N2CCCN(C)C.Cl. InChi Code: InChI=1S/C19H23ClN2.ClH/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22,/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3,1H. InChi Key: WIMWMKZEIBHDTH-UHFFFAOYSA-N.