Cinnamtannin B-1

Description: Cinnamtannin B-1 (LDN 0022358) is an A-type proanthocyanidin contained in several plant species such as Vaccinium vitis-idaea, Laurus nobilis L., Cinnamomum zeylanicum, and Lindera umbellata. It is a potent antioxidant and protective agent against oxidative stress and apoptosis in human platelets. It is a Cox-2 inhibitor. Target: Antioxidant, COX. Smiles: [H][C@@]12[C@@H](O)[C@@](Oc3cc(O)cc(O)c13)(Oc1cc(O)c3[C@@H]([C@@H](O)[C@H](Oc3c21)c1ccc(O)c(O)c1)c1c(O)cc(O)c2C[C@@H](O)[C@H](Oc12)c1ccc(O)c(O)c1)c1ccc(O)c(O)c1. References: Ito Y, Ohmori K, Suzuki K. Annulation approach to doubly linked (A-type) oligocatechins: syntheses of (+)-procyanidin A2 and (+)-cinnamtannin B1. Angew Chem Int Ed Engl. 2014 Sep 15,53(38):10129-33. doi: 10.1002/anie.201405600. Epub 2014 Jul 28. PubMed PMID: 25070773.