Chenodeoxycholic acid

Description: Chenodeoxycholic acid (CDCA) is a bile acid, usually conjugated with either glycine or taurine. It acts as a detergent to solubilize fats for intestinal absorption and is reabsorbed by the small intestine. It is used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones. Target: FXR, Autophagy, Endogenous Metabolite, Potassium Channel. Smiles: [H][C@@]12CC[C@H]([C@H](C)CCC(O)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])[C@H](O)CC2C[C@H](O)CC[C@]12C. References: Stauffer AT, et al. J Biol Chem,2002, 277(29), 26286-26292.