Casticin

Description: 1. Casticin (Vitexicarpin) can significantly reduce vascular inflammation, through inhibition of ROS-NF-kappaB pathway in vascular endothelial cells. 2. Casticin may become a potential leading drug in the therapy of prostate carcinoma. Target: STAT. Smiles: COc1ccc(cc1O)-c1oc2cc(OC)c(OC)c(O)c2c(=O)c1OC. References: Meng F M , Yang J B , Yang C H , et al. Vitexicarpin induces apoptosis in human prostate carcinoma PC-3 cells through G2/M phase arrest.[J]. Asian Pacific Journal of Cancer Prevention Apjcp, 2012, 13(12):6369.