Cardanol monoene

Cardanol monoene is a phenol found in cashew nut shell liquid that reversibly inhibits tyrosinase with an IC50 value of 56 µM in vitro. It halts the cell cycle at the S phase and inhibits proliferation dose- and time-dependently in M14 melanoma cells (IC50s = 23.15 and 12.30 µM after 24 and 48 hours of treatment, respectively). Cardanol monoene also induces apoptosis via the intrinsic pathway following the accumulation of reactive oxygen species (ROS). A mixture of cardanol mono-, di-, and triene is used to synthesize cardanol-metal complexes that inhibit uropathogenic E. coli biofilm formation.Formal Name: 3-8Z-pentadecen-1-yl-phenol. CAS Number: 501-26-8. Synonyms: Cardanol C15:1. Molecular Formula: C21H34O. Formula Weight: 302.5. Purity: >98%. Formulation: (Request formulation change), A neat oil. Solubility: DMF: 20 mg/ml, DMSO: 15 mg/ml, Ethanol: 22 mg/ml, Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml. lambdamax: 276 nm. SMILES: OC1=CC=CC(CCCCCCC/C=C\CCCCCC)=C1. InChi Code: InChI=1S/C21H34O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16-20-17-15-18-21(22)19-20/h7-8,15,17-19,22H,2-6,9-14,16H2,1H3/b8-7-. InChi Key: YLKVIMNNMLKUGJ-FPLPWBNLSA-N.