BRD32048

Description: BRD32048 is a top candidate ETV1 perturbagen. BRD32048 inhibits p300-dependent acetylation of ETV1, thereby promoting its degradation. Target: DNA/RNA Synthesis. Smiles: COc1ccc(Nc2nc(N)nc(CN3CCCCC3)n2)cc1. References: Kollareddy M, Sherrard A, Park JH, Szemes M, Gallacher K, Melegh Z, Oltean S, Michaelis M, Cinatl J Jr, Kaidi A, Malik K. The small molecule inhibitor YK-4-279 disrupts mitotic progression of neuroblastoma cells, overcomes drug resistance and synergizes with inhibitors of mitosis. Cancer Lett. 2017 Sep 10,403:74-85. doi: 10.1016/j.canlet.2017.05.027. Epub 2017 Jun 7. PubMed PMID: 28602975, PubMed Central PMCID: PMC5542135.