BI-3812

BI-3812 is an inhibitor of the oncogenic transcription factor Bcl-6 (IC50 = <3 nM). It inhibits the growth of NALM1, NALM6, Kasumi-2, and Kasumi-7 leukemia cells when used at concentrations of 3 and 10 µM.Formal Name: 1-[5-chloro-4-[[1,2-dihydro-8-methoxy-1-methyl-3-[2-(methylamino)-2-oxoethoxy]-2-oxo-6-quinolinyl]amino]-2-pyrimidinyl]-N,N-dimethyl-4-piperidinecarboxamide. CAS Number: 2166387-64-8. Molecular Formula: C26H32ClN7O5. Formula Weight: 558.0. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: Acetonitrile: Slightly soluble: 0.1-1 mg/ml. SMILES: O=C1C(OCC(NC)=O)=CC2=C(N1C)C(OC)=CC(NC3=NC(N4CCC(CC4)C(N(C)C)=O)=NC=C3Cl)=C2. InChi Code: InChI=1S/C26H32ClN7O5/c1-28-21(35)14-39-20-11-16-10-17(12-19(38-5)22(16)33(4)25(20)37)30-23-18(27)13-29-26(31-23)34-8-6-15(7-9-34)24(36)32(2)3/h10-13,15H,6-9,14H2,1-5H3,(H,28,35)(H,29,30,31). InChi Key: XCGYXEVLQIIEJH-UHFFFAOYSA-N.