beta-Cembrenediol

Description: beta-Cembrenediol (beta-CBT) is a natural product from tobacco plants that is found in cigarette smoke condensate. beta-CBT inhibits induction of the early antigen of Epstein-Barr virus (EA-EBV) by 12-O-tetradecanoylphorbol-13-acetate (TPA) in vitro (IC50 = 21.9 µM). It inhibits tumor promoting effects of TPA on 7,12-demethylbenz[a]anthracene-induced papilloma formation in vivo. beta-CBT is also released into soil by flue-cured tobacco plants and exerts autotoxicity as well as phytotoxic activity against L. sativa seedlings. Target: Others. Smiles: CC(C)[C@@H]1CC\C(C)=C/CC\C(C)=C/[C@H](O)C[C@@](C)(O)\C=C\1 , c:7,12,t:20,