BEC (hydrochloride)

BEC is a potent slow-binding competitive inhibitor of recombinant rat liver arginase I with Ki values of 0.4 and 0.6 µM from kinetic analyses. It is also a potent inhibitor of human arginase II with Ki values of 310 and 30 nM at pH 7.5 and 9.5, respectively. It does not inhibit murine iNOS at concentrations up to 1 mM. BEC significantly enhances nitric oxide-dependent relaxation of human penile corpus cavernosum smooth muscle in vitro when used at concentrations ranging from 0.1 to 1 mM.Formal Name: S-(2-boronoethyl)-L-cysteine, monohydrochloride. CAS Number: 222638-67-7. Molecular Formula: C5H12BNO4S . HCl. Formula Weight: 229.5. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: PBS (pH 7.2): 10 mg/ml. SMILES: OB(O)CCSC[C@@H](C(O)=O)N.Cl. InChi Code: InChI=1S/C5H12BNO4S.ClH/c7-4(5(8)9)3-12-2-1-6(10)11,/h4,10-11H,1-3,7H2,(H,8,9),1H. InChi Key: GHPYJLCQYMAXGG-UHFFFAOYSA-N.