AS19

Description: AS19 is a potent, selective 5-HT7 receptor agonist (IC50: 0.83 nM, Ki: 0.6 nM) with demonstrated selectivity for 5-HT7 over 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5A receptors (Kis: 89.7 nM, 490 nM, 6.6 nM, and 98.5 nM, respectively). Target: 5-HT Receptor. Smiles: CN(C)[C@H]1CCc2c(C1)cccc2-c1c(C)nn(C)c1C. References: Perez-García GS, et al. Effects of the potential 5-HT7 receptor agonist AS 19 in an autoshaping learning task. Behav Brain Res. 2005 Aug 30,163(1):136-40.