Araloside A

Description: Araloside A (Chikusetsusaponin IV) might relieve cutaneous symptoms caused by excessive apoptotic cell death in the skin through the Fas/FasL pathway. Target: RAAS, Fas/FasL. Smiles: [H][C@@]1(O[C@H]2[C@H](O)[C@@H](O)[C@]([H])(O[C@H]3CC[C@@]4(C)[C@@]([H])(CC[C@]5(C)[C@]4([H])CC=C4[C@]6([H])CC(C)(C)CC[C@@]6(CC[C@@]54C)C(=O)O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)C3(C)C)O[C@@H]2C(O)=O)O[C@@H](CO)[C@H](O)[C@H]1O. References: Hosononishiyama K , Matsumoto T , Kiyohara H , et al. Suppression of Fas-Mediated Apoptosis of Keratinocyte Cells by Chikusetsusaponins Isolated from the Roots of Panax japonicus[J]. Planta Medica, 2005, 72(03):193-198.