Apigenin 7-glucoside

Apigenin 7-glucoside is a flavonoid with anti-inflammatory and anxiolytic activities. It inhibits LPS-induced nitric oxide production in RAW 264.7 cells when used at concentrations ranging from 0.16 to 10 µM. In vivo, apigenin 7-glucoside (10 mg/kg) reduces pulmonary edema and lung inflammation in a mouse model of LPS-induced acute lung injury. It also increases the number of entries and the time spent in the open arms of the elevated plus maze in rats, indicating anxiolytic activity.Formal Name: 7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one. CAS Number: 578-74-5. Synonyms: 7-O-beta-D-Glucopyranosylapigenin, Apigenin-7-O-beta-D-glucoside, Apigetrin, Cosmosiin, NSC 407303. Molecular Formula: C21H20O10. Formula Weight: 432.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 3 mg/ml, DMSO: 5 mg/ml, PBS (pH 7.2): Partially soluble. lambdamax: 269, 336 nm. SMILES: O[C@H]1[C@H](OC2=CC(O)=C(C(C=C(C3=CC=C(O)C=C3)O4)=O)C4=C2)O[C@H](CO)[C@@H](O)[C@@H]1O. InChi Code: InChI=1S/C21H20O10/c22-8-16-18(26)19(27)20(28)21(31-16)29-11-5-12(24)17-13(25)7-14(30-15(17)6-11)9-1-3-10(23)4-2-9/h1-7,16,18-24,26-28H,8H2/t16-,18-,19+,20-,21-/m1/s1. InChi Key: KMOUJOKENFFTPU-QNDFHXLGSA-N. Origin: Plant/Sow thistle leaf.