Angelicin

Angelicin is a furanocoumarin typically isolated from the seeds of P. corylifolia. Like other furanocoumarins, angelicin has antibacterial activities against a number of Gram (+) and Gram (-) bacteria. It has also been shown to prevent tacrine-induced cytotoxicity in human liver-derived HepG2 cells (EC50 = 47 µg/ml) and vascular relaxation in phenylephrine-precontracted rat aorta. Angelicin also weakly inhibits topoisomerase II (IC50 = 404 µM).Formal Name: 2H-furo[2,3-h]-1-benzopyran-2-one. CAS Number: 523-50-2. Synonyms: Bakuchicin, NSC 404563. Molecular Formula: C11H6O3. Formula Weight: 186.2. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 2 mg/ml, DMSO: 5 mg/ml, DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml, Ethanol: 1 mg/ml. lambdamax: 247, 299 nm. SMILES: O=C1C=CC2=C(C(C=CO3)=C3C=C2)O1. InChi Code: InChI=1S/C11H6O3/c12-10-4-2-7-1-3-9-8(5-6-13-9)11(7)14-10/h1-6H. InChi Key: XDROKJSWHURZGO-UHFFFAOYSA-N. Origin: Plant/Psoralea corylifolia.