Alternariol

Alternariol is a mycotoxin, a toxic secondary fungal metabolite, produced by Alternaria molds. It is cytotoxic, fetotoxic, teratogenic, mutagenic, and genotoxic. It induces cytochrome P450 1A1 expression and apoptosis in mouse hepatoma cells (20-40 µM). Alternariol, whose synthesis is inhibited by light, naturally occurs on fruits, vegetables, and cereals, such as apples, tomatoes, and wheat.Formal Name: 3,7,9-trihydroxy-1-methyl-6H-dibenzo[b,d]pyran-6-one. CAS Number: 641-38-3. Synonyms: AOH, NSC 638263. Molecular Formula: C14H10O5. Formula Weight: 258.2. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 30 mg/ml, DMSO: 30 mg/ml, DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml, Ethanol: 0.5 mg/ml. lambdamax: 257, 289, 301, 342 nm. SMILES: CC1=C(C2=C(C(O3)=O)C(O)=CC(O)=C2)C3=CC(O)=C1. InChi Code: InChI=1S/C14H10O5/c1-6-2-7(15)5-11-12(6)9-3-8(16)4-10(17)13(9)14(18)19-11/h2-5,15-17H,1H3. InChi Key: CEBXXEKPIIDJHL-UHFFFAOYSA-N.