alpha-Spinasterol

Description: alpha-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects. alpha-Spinasterol inhibits COX-1 andCOX-2 activities with IC50 values of 16.17 µM and 7.76 µM, respectively. Target: TRP/TRPV Channel, Antibacterial, COX. Smiles: [H][C@@]12CC[C@H]([C@H](C)\C=C\[C@@H](CC)C(C)C)[C@@]1(C)CC[C@@]1([H])C2=CC[C@@]2([H])C[C@@H](O)CC[C@]12C. References: Indiara, Brusco, Camila, et al. alpha-Spinasterol: a COX inhibitor and a transient receptor potential vanilloid 1 antagonist presents an antinociceptive effect in clinically relevant models of pain in mice.[J]. British Journal of Pharmacology, 2017.