alpha-CEHC

Molecules having vitamin E antioxidant activity include four tocopherols (alpha, beta, delta, and gamma) and four tocotrienols (alpha, beta, delta, and gamma). alpha-Tocopherol is the major lipid soluble antioxidant in vivo and protects against lipid peroxidation. alpha-CEHC is the major urinary metabolite of alpha-tocopherol following vitamin E supplementation. The concentration of alpha-CEHC in human serum is in the range of 5-10 pmol/ml but increases significantly up to 200 pmol/ml upon supplementation with RRR-alpha-tocopherol. About one-third of the alpha-CEHC circulating in the blood is present as a glucuronide conjugate. alpha-CEHC was only excreted when a threshold concentration of 7-9 µmol alpha-tocopherol/g total lipid in plasma was exceeded. Therefore, excretion of alpha-CEHC may be considered to be a marker of optimum vitamin E intake.Formal Name: 3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-propanoic acid. CAS Number: 4072-32-6. Molecular Formula: C16H22O4. Formula Weight: 278.3. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, DMSO:PBS (pH 7.2)(1:1): .25 mg/ml, Ethanol: 10 mg/ml. lambdamax: 206, 291 nm. SMILES: CC1=C(OC(CCC(O)=O)(C)CC2)C2=C(C)C(O)=C1C. InChi Code: InChI=1S/C16H22O4/c1-9-10(2)15-12(11(3)14(9)19)5-7-16(4,20-15)8-6-13(17)18/h19H,5-8H2,1-4H3,(H,17,18). InChi Key: AXODOWFEFKOVSH-UHFFFAOYSA-N.