Aloesin

Aloesin is a C-glycosylated chromone compound found in aloe (Liliaceae) that inhibits tyrosinase (IC50 = 0.9 mM), an enzyme responsible for catalyzing the first step of the conversion of tyrosine to melanin. Derivatives of aloesin have been shown to exhibit free radical scavenging and anti-inflammatory activity. The antihyperpigmenting effects of aloesin have been explored in melanocytes.Formal Name: 8-beta-D-glucopyranosyl-7-hydroxy-5-methyl-2-(2-oxopropyl)-4H-1-benzopyran-4-one. CAS Number: 30861-27-9. Molecular Formula: C19H22O9. Formula Weight: 394.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 20 mg/ml, DMSO: 20 mg/ml, Ethanol: 10 mg/ml, PBS (pH 7.2): 5 mg/ml. lambdamax: 215, 245, 253, 295 nm. SMILES: O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](C2=C(OC(CC(C)=O)=CC3=O)C3=C(C)C=C2O)[C@@H]1O. InChi Code: InChI=1S/C19H22O9/c1-7-3-10(22)14(19-17(26)16(25)15(24)12(6-20)28-19)18-13(7)11(23)5-9(27-18)4-8(2)21/h3,5,12,15-17,19-20,22,24-26H,4,6H2,1-2H3/t12-,15-,16+,17-,19+/m1/s1. InChi Key: HKIKAXXIWJHWLY-ZIIYPAMZSA-N.