Alitame

Alitame is a synthetic dipeptide non-caloric sweetener. It binds to the Venus fly trap domain of the class 1 sweet taste receptor subunit TAS1R2 (Kd = 0.15 µM for the recombinant human receptor). It substitutes for sucrose in the two-bottle preference test in non-human primates. Formulations containing alitame have been used as sweetening agents and flavor enhancers in foods and beverages.Formal Name: L-alpha-aspartyl-N-(2,2,4,4-tetramethyl-3-thietanyl)-D-alaninamide. CAS Number: 80863-62-3. Synonyms: CP 54,802. Molecular Formula: C14H25N3O4S. Formula Weight: 331.4. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: 10 mg/ml, DMSO: 10 mg/ml, Ethanol: 10 mg/ml, PBS (pH 7.2): 10 mg/ml. SMILES: O=C([C@@H](C)NC([C@@H](N)CC(O)=O)=O)NC(C1(C)C)C(C)(S1)C. InChi Code: InChI=1S/C14H25N3O4S/c1-7(16-11(21)8(15)6-9(18)19)10(20)17-12-13(2,3)22-14(12,4)5/h7-8,12H,6,15H2,1-5H3,(H,16,21)(H,17,20)(H,18,19)/t7-,8+/m1/s1. InChi Key: IVBOUFAWPCPFTQ-SFYZADRCSA-N.