AFP-07 free acid

Description: AFP 07 free acid is a 7,7-difluoroprostacyclin derivative. It also acts as a selective and highly potent agonist for the IP receptor. Target: Others. Smiles: C(=C/[C@H]([C@H](CC#CCC)C)O)\[C@@H]1[C@@]2([C@@](O/C(=C\CCCC(O)=O)/C2(F)F)(C[C@H]1O)[H])[H]. References: McCormick C, Jones RL, Kennedy S, Wadsworth RM. Activation of prostanoid EP receptors by prostacyclin analogues in rabbit iliac artery: implications for anti-restenotic potential. Eur J Pharmacol. 2010 Sep 1,641(2-3):160-7. doi: 10.1016/j.ejphar.2010.04.035. Epub 2010 May 5. PubMed PMID: 20450909.