Acetyl-L-carnitine hydrochloride

Description: Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) is a nutritional supplement composed of the hydrochloride salt form of the acetylated form of the endogenously produced L-carnitine, with potential neuroprotective, cognitive-enhancing, anti-depressive and immunomodulating activities. It may also relieve peripheral neuropathy induced by chemotherapy, diabetes or other diseases. In addition, acetyl-L-carnitine may modulate the immune response by increasing T-lymphocytes maturation and may downregulate pro-inflammatory cytokines in response to viruses, such as SARS-CoV-2. It may also disrupt the ACE2 signaling pathway and inhibit the production of reactive oxygen species (ROS). Target: Others, Endogenous Metabolite. Smiles: [Cl-].CC(=O)O[C@H](CC(O)=O)C[N+](C)(C)C. References: Stephens, F., Constantin-Teodosiu, D., & Greenhaff, P. (2007). New insights concerning the role of carnitine in the regulation of fuel metabolism in skeletal muscle. The Journal Of Physiology, 581(2), 431-444. doi: 10.1113/jphysiol.2006.125799