ABT 724 trihydrochloride

Description: ABT 724 trihydrochloride is an effective and selective agonist of the D4 receptor (EC50 = 12.4 nM, 14.3 nM, and 23.2 nM for human, rat and ferret, respectively). ABT-724 trihydrochloride can be used in erectile dysfunction studies. Target: Dopamine Receptor. Smiles: N1(C2=CC=CC=N2)CCN(CC3=NC4=CC=CC=C4N3)CC1.Cl.Cl.Cl. References: Brioni JD, et al. Activation of dopamine D4 receptors by ABT-724 induces penile erection in rats. Proc Natl Acad Sci U S A. 2004 Apr 27,101(17):6758-63.