6-PPD-quinone

6-PPD-quinone is an oxidized derivative of the tire antiozonant and substituted p-phenylenediamine 6-PPD (Cay-38246). It is toxic to rainbow trout (O. mykiss) and brook trout (S. fontinalis, LC50s = 0.59 and 1.96 µg/L, respectively) but not to arctic char (S. alpinus) and white sturgeon (A. transmontanus, LC50s = >12.7 µg/L for both). 6-PPD-quinone (10 µg/L) induces cell death and germline DNA damage, as well as decreases the number of mitotic cells, in C. elegans gonads. Urine levels of 6-PPD-quinone are increased in pregnant women compared to non-pregnant adults and children.Formal Name: 2-[(1,3-dimethylbutyl)amino]-5-(phenylamino)-2,5-cyclohexadiene-1,4-dione. CAS Number: 2754428-18-5. Synonyms: 6-PPDQ. Molecular Formula: C18H22N2O2. Formula Weight: 298.4. Purity: >95%. Formulation: (Request formulation change), A solid. Solubility: DMF: Soluble, Methanol: Soluble. lambdamax: 253, 354 nm. SMILES: CC(CC(C)C)NC1=CC(C(NC2=CC=CC=C2)=CC1=O)=O. InChi Code: InChI=1S/C18H22N2O2/c1-12(2)9-13(3)19-15-10-18(22)16(11-17(15)21)20-14-7-5-4-6-8-14/h4-8,10-13,19-20H,9H2,1-3H3. InChi Key: UBMGKRIXKUIXFQ-UHFFFAOYSA-N.